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CHEMOTHERAPY OF PSORIASIS: TEN YEARS OF EXPERIENCE
Author(s) -
MOSCHELLA SAMUEL L.
Publication year - 1976
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1976.tb01813.x
Subject(s) - psoriasis , medicine , methotrexate , chemotherapy , dermatology , oncology , surgery
The hunt for an effective, easier to administer, more acceptable therapeutic modality for extensive chronic psoriasis continues. The chemotherapy of psoriasis is reviewed in 246 patients from 1964 to 1974 treated with methotrexate, 92 patients from 1971 to 1974 with hydroxyurea, and 36 patients from 1972 to 1974 with azaribine. Currently, the available chemotherapy agents are the least palatable and desirable form of treatment. Methotrexate continues to be the most predictable, effective and hast expensive. The use of photo‐chemotherapy may prove to be more effective, less toxic, and more practical until a more specific and effective etiologically directed form of therapy becomes available.