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TREATMENT OF HYPERHIDROSIS WITH TOPICAL METHENAMINE
Author(s) -
BERCSTRESSER PAUL R.,
QUERO ROBERTO
Publication year - 1976
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1976.tb00240.x
Subject(s) - medicine , sweat , hyperhidrosis , dermatology , surgery , formaldehyde , chemistry , organic chemistry
idiopathic palmar and plantar hyperhidrosis is a relatively common disor‐der of eccrine sweat gland function. Treat‐ment with glufaraldehyde or formaldehyde, although successful, may cause undesirable side effects. Methenamine is a polycyclic organic compound which releases ammonia and formaldehyde at acid pH. Five per cent methenamine in a firm slick gel, applied daily to one palmar or plantar surface of 109 patients with hyperhidrosis, resulted in significantly less sweating after one month. No patients were sensitized to formaldehyde.