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Breed‐associated phenotypes in canine atopic dermatitis
Author(s) -
Wilhem Sylvia,
Kovalik Marcel,
Favrot Claude
Publication year - 2011
Publication title -
veterinary dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.744
H-Index - 60
eISSN - 1365-3164
pISSN - 0959-4493
DOI - 10.1111/j.1365-3164.2010.00925.x
Subject(s) - breed , atopic dermatitis , phenotype , population , clinical phenotype , medicine , disease , presentation (obstetrics) , dermatology , biology , genetics , pathology , environmental health , radiology , gene
Canine atopic dermatitis is a multifaceted disease, whose clinical presentation may be affected by numerous factors, including the genetic background of the animal, the environment, the offending allergens and flare factors. In particular, breed‐associated differences have often been mentioned but never defined precisely. Using a large data set of atopic dogs, we document in this study the clinical presentation of nine often‐affected breeds and demonstrate the existence of substantial differences between the clinical phenotype of each breed and the whole population. Some of the differences may be due to genetic differences while others are most likely to be associated with variations in environmental factors.