Premium
CNS and lung metastasis of sebaceous epithelioma in a dog
Author(s) -
Bettini Giuliano,
Morini Maria,
Mandrioli Luciana,
Capitani Ombretta,
Gandini Gualtiero
Publication year - 2009
Publication title -
veterinary dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.744
H-Index - 60
eISSN - 1365-3164
pISSN - 0959-4493
DOI - 10.1111/j.1365-3164.2009.00762.x
Subject(s) - epithelioma , medicine , sebaceous carcinoma , pathological , malignancy , lung , metastasis , carcinoma , pathology , cancer
Sebaceous epithelioma is a common canine cutaneous neoplasm characterized by a preponderance of basaloid cells with few well‐differentiated sebocytes. It is considered a low‐grade malignancy, as it may occasionally recur at the excision site; the possibility of lymph node metastasis is anecdotally reported, and distant metastases have never been observed. This case report presents the clinical and pathological features of a sebaceous epithelioma of the upper lip with a highly aggressive behaviour. The patient was a 9‐year‐old female dachshund that developed local recurrence 11 months after the excision of the primary sebaceous epithelioma and multiple lung and central nervous system metastases 5 months later. The designation epitheliomatous sebaceous carcinoma has been suggested for aggressive sebaceous epitheliomas, although differential criteria are still to be determined.