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Factores de riesgo para la incidencia del virus del dengue en niños en edad preescolar
Author(s) -
Teixeira Maria G.,
Morato Vanessa,
Barreto Florisneide R.,
Mendes Carlos M. C.,
Barreto Maurício L.,
Costa Maria da Conceição N.
Publication year - 2012
Publication title -
tropical medicine and international health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 114
eISSN - 1365-3156
pISSN - 1360-2276
DOI - 10.1111/j.1365-3156.2012.03086.x
Subject(s) - dengue fever , medicine , seroprevalence , logistic regression , dengue virus , incidence (geometry) , epidemiology , environmental health , demography , population , public health , serology , pediatrics , virology , immunology , antibody , physics , optics , nursing , sociology
Objective To estimate the seroincidence of dengue in children living in Salvador, Bahia, Brazil and to evaluate the factors associated. Methods A prospective serological survey was carried out in a sample of children 0–3 years of age. A multilevel logistic model was used to identify the determinants of seroincidence. Results The seroprevalence of dengue was 26.6% in the 625 children evaluated. A second survey detected an incidence of 33.2%. Multilevel logistic regression showed a statistically significant association between the seroincidence of dengue and age and the premises index. Conclusion In Salvador, the dengue virus is in active circulation during early childhood; consequently, children have heterotypic antibodies and run a high risk of developing dengue haemorrhagic fever, because the sequence and intensity of the three dengue virus serotypes currently circulating in this city are very similar to those that were circulating in Rio de Janeiro, Brazil, in 2008. Therefore, the authors strongly recommend that the health authorities in cities with a similar epidemiological scenario be aware of this risk and implement improvements in health care, particularly targeting the paediatric age groups. In addition, information should be provided to the population and actions should be implemented to combat this vector.