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Nivel de susceptibilidad de los vectores de malaria a los insecticidas comúnmente utilizados para el control de la malaria en Tanzania
Author(s) -
Kabula Bilali,
Tungu Patrick,
Matowo Johnson,
Kitau Jovin,
Mweya Clement,
Emidi Basiliana,
Masue Denis,
Sindato Calvin,
Malima Robert,
Minja Jubilate,
Msangi Shandala,
Njau Ritha,
Mosha Franklin,
Magesa Stephen,
Kisinza William
Publication year - 2012
Publication title -
tropical medicine and international health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 114
eISSN - 1365-3156
pISSN - 1360-2276
DOI - 10.1111/j.1365-3156.2012.02986.x
Subject(s) - permethrin , deltamethrin , malaria , tanzania , pyrethroid , toxicology , biology , environmental health , anopheles gambiae , insecticide resistance , mortality rate , veterinary medicine , pesticide , medicine , socioeconomics , immunology , ecology , surgery , sociology
Objective The aim of the study was to monitor the insecticide susceptibility status of malaria vectors in 12 sentinel districts of Tanzania. Methods WHO standard methods were used to detect knock‐down and mortality in the wild female Anopheles mosquitoes collected in sentinel districts. The WHO diagnostic doses of 0.05% deltamethrin, 0.05% lambdacyhalothrin, 0.75% permethrin and 4% DDT were used. Results The major malaria vectors in Tanzania, Anopheles gambiae s.l., were susceptible (mortality rate of 98–100%) to permethrin, deltamethrin, lambdacyhalothrin and DDT in most of the surveyed sites. However, some sites recorded marginal susceptibility (mortality rate of 80–97%); Ilala showed resistance to DDT (mortality rate of 65% [95% CI, 54–74]), and Moshi showed resistance to lambdacyhalothrin (mortality rate of 73% [95% CI, 69–76]) and permethrin (mortality rate of 77% [95% CI, 73–80]). Conclusions The sustained susceptibility of malaria vectors to pyrethroid in Tanzania is encouraging for successful malaria control with Insecticide‐treated nets and IRS. However, the emergency of focal points with insecticide resistance is alarming. Continued monitoring is essential to ensure early containment of resistance, particularly in areas that recorded resistance or marginal susceptibility and those with heavy agricultural and public health use of insecticides.