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Comunicación corta: Diferentes espectros de la enfermedad oftálmica asociada al VIH entre pacientes que comienzan la terapia antirretroviral en India y Sudáfrica.
Author(s) -
Pathai Sophia,
Gilbert Clare,
Weiss Helen A.,
McNally Matthew,
Lawn Stephen D.
Publication year - 2011
Publication title -
tropical medicine and international health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 114
eISSN - 1365-3156
pISSN - 1360-2276
DOI - 10.1111/j.1365-3156.2010.02712.x
Subject(s) - antiretroviral therapy , medicine , human immunodeficiency virus (hiv) , optometry , virology , viral load
Summary Differences in the prevalence and spectrum of HIV‐associated ophthalmic disease in Africa and Asia are not well documented. We studied two comparable cohorts of patients initiating antiretroviral therapy in Mumbai, India, and Cape Town, South Africa. The prevalence of HIV‐associated ophthalmic disease was higher in the Indian population (17.5%) than in the South African population (12.1%). This was largely because of vitreo‐retinal opportunistic infections (11.4% vs . 2.6%, respectively), notably cytomegalovirus retinitis. This difference persisted after adjusting for confounding factors (adjusted odds ratio = 11.32, 95% confidence interval: 2.67–48.13), confirming a marked geographical difference in the prevalence of HIV‐associated retinal disease.