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Estimación de la carga global de secuelas no supurativas de infecciones del tracto respiratorio superior: fiebre reumática y glomerulonefritis postestreptocócica
Author(s) -
Jackson Stewart J.,
Steer Andrew C.,
Campbell Harry
Publication year - 2011
Publication title -
tropical medicine and international health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 114
eISSN - 1365-3156
pISSN - 1360-2276
DOI - 10.1111/j.1365-3156.2010.02670.x
Subject(s) - medicine , rheumatic fever , incidence (geometry) , acute rheumatic fever , mortality rate , disease , indigenous , disease burden , pediatrics , immunology , physics , optics , ecology , biology
Summary Objectives To establish the incidence of post‐streptococcal glomerulonephritis (PSGN) and acute rheumatic fever, the prevalence of rheumatic heart disease (RHD), and to estimate morbidity and mortality caused by these diseases globally. Methods Systematic literature review and review of World Health Organisation (WHO) vital registration data (VRD). Results Incidence and prevalence of rheumatic fever and RHD show very significant global variation. The greatest burden was found in sub‐Saharan Africa, the lowest in North America. The highest mortality rates from these two diseases were reported in the indigenous populations of Australia (23.8 per 100 000). Among countries with VRD, the highest mortality was found in Mauritius (4.32 per 100 000). A few studies reported mortality from PSGN and these reported low mortality rates (mean 0.028 per 100 000 in developing countries). Conclusion Lack of data from key parts of the world limits our ability to make precise statements of disease burden. Further research and surveillance is required to generate more primary data to inform future estimates.