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Leishmaniasis en Turquía: caracterización molecular de Leishmania provenientes de muestras clínicas humanas y caninas
Author(s) -
Toz Seray Ozensoy,
Nasereddin Abedelmajeed,
Ozbel Yusuf,
Ertabaklar Hatice,
Culha Gulnaz,
Sevil Naser,
Ziya Alkan M.,
Jaffe Charles L.
Publication year - 2009
Publication title -
tropical medicine and international health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 114
eISSN - 1365-3156
pISSN - 1360-2276
DOI - 10.1111/j.1365-3156.2009.02384.x
Subject(s) - leishmania infantum , visceral leishmaniasis , canine leishmaniasis , leishmaniasis , leishmania , cutaneous leishmaniasis , leishmania tropica , parasitic disease , human disease , biology , infectious disease (medical specialty) , leishmania major , disease , immunology , virology , medicine , parasite hosting , pathology , world wide web , computer science
Summary Human leishmaniasis, both visceral and cutaneous, and canine leishmaniasis have been reported in Turkey for centuries. However, the advent of new diagnostic tools during the last 30 years has led to the recognition that leishmaniasis is an important public health problem throughout the country. In most disease foci both canine and human leishmaniases exist together and identification of parasite species causing these diseases is a pre‐requisite for understanding disease epidemiology. A total of 109 samples obtained from human and canine leishmaniasis cases were examined using internal transcribed spacer 1 PCR followed by restriction fragment length polymorphism analysis. Our results indicate that two species, Leishmania tropica and Leishmania infantum, are primarily responsible for cutaneous and visceral leishmaniasis, respectively, in Turkey. However, a new focus of human cutaneous leishmaniasis caused by L. infantum in Hatay region is described. This finding further stresses the importance of Leishmania species molecular characterization in prescribing appropriate therapy and understanding the disease’s transmission in different endemic foci.