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Filogenia del virus del dengue tipo 3 circulando en Colombia entre el 2001 y el 2007
Author(s) -
VillabonaArenas Christian Julián,
MirandaEsquivel Daniel Rafael,
Jimenez Raquel Elvira Ocazionez
Publication year - 2009
Publication title -
tropical medicine and international health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 114
eISSN - 1365-3156
pISSN - 1360-2276
DOI - 10.1111/j.1365-3156.2009.02339.x
Subject(s) - dengue virus , panama , dengue fever , latin americans , geography , molecular epidemiology , genotype , phylogenetic tree , phylogenetics , virology , biology , ecology , gene , genetics , linguistics , philosophy
Summary Dengue virus type 3 (DENV‐3) re‐appeared in Colombia in 2001 after 23 years of apparent absence, in the state of Santander in the North‐eastern region near to Venezuelan border. In 2002, the virus was isolated in the state of Valle del Cauca in the South‐east region near to Ecuadorian/Peruvian border, and in the state of Antioquia in the North‐east region near to Panama border. To gain insight into the molecular epidemiology of DENV‐3 in Colombia, we sequenced the complete E gene of 21 isolates sampled in the period 2001–2007. Phylogenetic analyses revealed that Colombian strains seem to have been introduced from Venezuela, Ecuador and Peru, but not from Brazil, Argentina, Paraguay or Central America countries. This study also confirms previous report showing that Colombian isolates is closely related to DENV‐3 genotype III.