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Tratamiento Preventivo Intermitente de malaria en lactantes: como funciona y donde funcionará?
Author(s) -
Gosling R. D.,
Carneiro I.,
Chandramohan D.
Publication year - 2009
Publication title -
tropical medicine and international health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 114
eISSN - 1365-3156
pISSN - 1360-2276
DOI - 10.1111/j.1365-3156.2009.02303.x
Subject(s) - malaria , medicine , transmission (telecommunications) , public health , environmental health , intensive care medicine , immunology , nursing , computer science , telecommunications
Summary We discuss the potential public health impact of IPTi by estimating the cases of malaria, anaemia and hospital admissions likely to be averted in different transmission settings; and we review the mechanism of action, choice of drugs regimens, and the effect on immunity of IPTi. IPTi using an efficacious drug is likely to substantially reduce cases of clinical malaria in moderate to high transmission settings. However, geographical heterogeneity in malaria transmission could hamper rolling out IPTi as a national policy.