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Evaluación del inmunodiagnóstico de Toxocariasis en Cisticercosis Porcina Experimental
Author(s) -
García Hector H.,
Cancrini Gabriella,
Bartalesi Filippo,
Rodriguez Silvia,
Jimenez Juan A.,
Roldan William,
Mantella Antonia,
Nicoletti Alessandra,
Bartoloni Alessandro
Publication year - 2007
Publication title -
tropical medicine and international health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 114
eISSN - 1365-3156
pISSN - 1360-2276
DOI - 10.1111/j.1365-3156.2006.01757.x
Subject(s) - cysticercosis , taenia solium , toxocara canis , serology , biology , toxocariasis , virology , helminthiasis , immunology , toxocara cati , antibody , helminths , zoology
Summary We assessed whether immunodiagnostic tests for cysticercosis can cross‐react with the currently available immunodiagnostic tests for Toxocara canis in an established animal model for cysticercosis infection in pigs, known host for Toxocara . We examined by TES‐enzyme‐linked immunosorbent test and immunoblot assay for toxocarosis and cysticercosis the baseline and final follow‐up sera of 10 pigs, before and after (3 months) infection with Taenia solium . After successful cysticercosis infection, the nine evaluable pigs became seropositive to T. solium (enzyme‐linked immunoelectrotransfer blot assay), but did remain seronegative for Toxocara in both assays, documenting the lack of cross‐reactivity with anti‐ T. solium antibodies in both T. canis assays. These findings should help clinicians better interpret serology for toxocariosis and cysticercosis in endemic areas for both helminth infections.