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Linaje 1 de Trypanosoma cruzi en una biopsia endomiocardial
Author(s) -
Teixeira Marta M. G.,
Silva Flávia Maia,
Marcili Arlei,
Umezawa Eufrosina S,
ShikanaiYasuda Maria A,
CunhaNeto Edécio,
Kalil Jorge,
Stolf Noedir,
Stolf Anna Maria S
Publication year - 2006
Publication title -
tropical medicine and international health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 114
eISSN - 1365-3156
pISSN - 1360-2276
DOI - 10.1111/j.1365-3156.2006.01575.x
Subject(s) - trypanosoma cruzi , chagas disease , cardiomyopathy , neglected tropical diseases , trypanosomiasis , endomyocardial biopsy , medicine , biopsy , lineage (genetic) , disease , myocarditis , immunology , heart failure , cardiology , biology , genetics , gene , parasite hosting , world wide web , computer science
Summary Trypanosoma cruzi , the agent of Chagas disease, is genetically classified into two major evolutionary lineages, T. cruzi I and T. cruzi II. In Southern American Cone countries it is T cruzi II which causes most cases of severe chronic Chagas disease. Contrary to this, we isolated T. cruzi I nested in endomyocardial biopsies of a chronic chagasic patient with end‐stage heart failure. Our finding should alert clinicians to the possibility of severe Chagas disease in all regions where T. cruzi circulates, regardless of its lineage.