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Spectrum of neuropsychiatric complications in 791 cases of typhoid fever
Author(s) -
Ali Gazanfar,
Rashid Samia,
Kamli M. A.,
Shah Parvez A.,
Allaqaband G. Q.
Publication year - 1997
Publication title -
tropical medicine and international health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 114
eISSN - 1365-3156
pISSN - 1360-2276
DOI - 10.1111/j.1365-3156.1997.tb00145.x
Subject(s) - medicine , typhoid fever , encephalitis , parkinsonism , myelitis , pediatrics , delirium , polymyositis , poliomyelitis , polyneuropathy , surgery , immunology , disease , pathology , psychiatry , spinal cord , virus
Summary Over a 6‐year period, we studied 791 patients with multidrug‐resistant typhoid fever, of whom 665 individuals (84%) developed neuropsychiatric manifestations. These were: acute confusional state (73%); myelitis (6%); cerebellitis (1%); parkinsonism (1%); acute psychosis (0.6%); meningo‐encephalitis (0.5%); encephalitis (0.25%); sensory motor polyneuropathy, polymyositis, acute schizophrenia and bizarre neurological syndromes (0.12% each). Severe parkinsonian rigidity and meningo‐encephalitis are associated with significant morbidity but very low mortality (0.5%).