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Prevention of snail miracidia interactions using Phytolacca dodecandra (L'Herit) (endod) as a miracidiacide: an alternative approach to the focal control of schistosomiasis
Author(s) -
Madhina D.,
Shift C.
Publication year - 1996
Publication title -
tropical medicine and international health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 114
eISSN - 1365-3156
pISSN - 1360-2276
DOI - 10.1111/j.1365-3156.1996.tb00030.x
Subject(s) - toxicant , molluscicide , snail , biology , schistosomiasis , infectivity , schistosoma mansoni , veterinary medicine , helminthiasis , schistosoma , transmission (telecommunications) , intermediate host , schistosoma haematobium , toxicology , microbiology and biotechnology , helminths , immunology , ecology , toxicity , host (biology) , medicine , virus , electrical engineering , engineering
Summary The effect of endod berry extract against schistosome miracidia has been tested to determine the sensitivity of these organisms to the molluscicide and to see whether miracidia subjected to sublethal doses of the toxicant will be able to infect their specific host snails. Short contact (30 min) LC 50 of endod extract with miracidia of Schistosoma mansoni was 8.2 parts per million (p.p.m.) (95% CL 5–13). However, exposure of S. haematobium to sublethal doses of 3 p.p.m. for 30 min or overnight in open air ponds reduced their infectivity 3.5‐5.6‐fold when compared with controls. It is suggested that the toxicant could be used in low doses at transmission foci to reduce schistosome infection in snails. This could be done by using a controlled release system to apply the toxicant material at such foci where transmission is likely to occur.