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Packed red blood cell age does not impact adverse events or outcomes after subarachnoid haemorrhage
Author(s) -
Naidech A. M.,
Liebling S. M.,
Duran I. M.,
Ault M. L.
Publication year - 2011
Publication title -
transfusion medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.471
H-Index - 59
eISSN - 1365-3148
pISSN - 0958-7578
DOI - 10.1111/j.1365-3148.2010.01048.x
Subject(s) - medicine , packed red blood cells , adverse effect , modified rankin scale , anesthesia , subarachnoid hemorrhage , respiratory distress , blood transfusion , surgery , ischemic stroke , ischemia
Objectives: To determine if the age of packed red blood cells (PRBCs) is associated with adverse events or outcomes in patients with subarachnoid haemorrhage (SAH). Aim: Analyse data on PRBC age to complications and outcomes in patients with SAH. Background: Patients who receive a PRBC transfusion after SAH have a higher rate of complications, and older PRBC age may be responsible for this. Methods/Materials: We prospectively recorded clinical and demographic data, acute adverse effects related to transfusion, major hospital events, radiographic cerebral infarction, PRBC age and outcomes in 119 patients with SAH who received a PRBC transfusion. Patients were followed for outcomes at 14 days or discharge, 28 days and 3 months with the modified Rankin scale (a measure of neurologic function). Results: In 241 PRBC transfusions, there was new fever in 36 (15%), hypotension in 23 (10%), pulmonary oedema or symptomatic respiratory distress in 5 (2%) and rash in 1 (1%). Age of PRBCs administered was not associated with vasospasm, cerebral infarction, acute adverse events or outcomes ( P > 0·1 for all). Conclusions: In this small registry of patients with SAH, the age of transfused PRBCs was not associated with adverse events or outcomes.