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Stem Cell Collection in a Patient with Cold Agglutinins
Author(s) -
Collins David,
Antonenas Vicki
Publication year - 2005
Publication title -
transfusion medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.471
H-Index - 59
eISSN - 1365-3148
pISSN - 0958-7578
DOI - 10.1111/j.1365-3148.2005.00554az.x
Subject(s) - cold agglutinin , lymphoma , stem cell , medicine , transplantation , intensive care medicine , surgery , immunology , biology , antibody , genetics
The use of autologous Bone Marrow Transplant (BMT) has increased in Non Hodgkin’s Lymphoma. A patient, who had a relapse of Non Hodgkin’s Lymphoma after a remission of 13 years, required an autologous stem cell transplant. However, he was found to have cold agglutinins. The problem was raised as to whether or not he could have stem cells collected and if they would survive following freezing and storage. A literature search was undertaken and very little information found on stem cell collection in patients with cold agglutinins. Some anecdotal information was reported by colleagues all of which seemed to point to less than favourable outcomes. It was decided to mobilize the patient for stem cell collection and devise a method of collection, storage and transplantation. This paper will give an account of the collection, treatment and progress of the patient, and discuss the procedures involved. It will demonstrate the collaboration between medical, nursing and laboratory staff to achieve a positive patient outcome.