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The IgA‐deficient blood donor: something in the air?
Author(s) -
Munks R.
Publication year - 1996
Publication title -
transfusion medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.471
H-Index - 59
eISSN - 1365-3148
pISSN - 0958-7578
DOI - 10.1111/j.1365-3148.1996.tb00080.x
Subject(s) - iga deficiency , abo blood group system , medicine , blood grouping , antibody , blood transfusion , immunology , blood donations , immunoglobulin e , immunoglobulin a , blood typing , immunoglobulin g
Summary. In May 1994, the Blood Transfusion Centre, Sheffield, introduced a new screening test for Immunoglobulin A (IgA) deficiency. The test is performed in parallel with routine donor ABO grouping and Rh typing on two Olympus PK 7200 autoanalysers. A panel of IgA‐deficient donors is required to provide blood products for IgA‐deficient patients in whom the presence of anti‐IgA antibodies may cause serious anaphylactic transfusion reactions (Welborn & Hersch, 1991). Detection rates during high summer became noticeably inconsistent and since a relationship between IgA deficiency and hypersensitivity states is recognized (Amman & Hong, 1971), a comparison between the detection rate and pollen levels during June and July 1994 was undertaken; the results of this study are presented here.