Premium
In‐line filtration of platelet concentrates obtained with the Omnix TM blood cell separator
Author(s) -
Moog R.,
Müller N.,
Nieper A.
Publication year - 1995
Publication title -
transfusion medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.471
H-Index - 59
eISSN - 1365-3148
pISSN - 0958-7578
DOI - 10.1111/j.1365-3148.1995.tb00218.x
Subject(s) - platelet , blood product , filtration (mathematics) , apheresis , chromatography , plateletpheresis , blood cell , chemistry , white blood cell , medicine , immunology , surgery , mathematics , statistics
SUMMARY. The quality of platelet concentrates (PC) obtained with the blood cell separator Omnix TM was investigated before and after in‐line filtration. PC were filtered 2h (protocol A) and 4h (protocol B) after the termination of apheresis. Platelet (PLT) yield after filtration was similar in both protocols (median 3.7 vs. 3.4 times 10 11 ). Median white blood cell (WBC) contamination after leucocyte depletion was 0.07 times 10 6 (range 0.02–3.27 times 10 6 ) in protocol A and 0.06 times 10 6 (range 0.02–2.1 times 10 6 ) in protocol B. Glucose, lactate, lactate dehydrogenase, morphology score and pH value were not statistically different before and after filtration in both protocols. We conclude that in‐line filtration results in sufficient leucocyte depletion of the PC. The prefiltration storage time did not influence the studied parameters of product quality.