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Further complexities of the Rh antigen D disclosed by testing category D II cells with monoclonal anti‐D
Author(s) -
Lomas C.,
McColl K.,
Tippett P.
Publication year - 1993
Publication title -
transfusion medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.471
H-Index - 59
eISSN - 1365-3148
pISSN - 0958-7578
DOI - 10.1111/j.1365-3148.1993.tb00106.x
Subject(s) - monoclonal antibody , antigen , monoclonal , microbiology and biotechnology , medicine , immunology , biology , antibody
Summary: The reaction pattern of monoclonal anti‐D with category D II cells differed from those of other category D cells. D II cells express epDl, epD2, epD3, epD5, epD6/7 and epD8 but lack epD4 and a new epitope epD9. The new epitope, epD9, is proposed to explain the failure of some monoclonal anti‐D (previously considered to be anti‐epD3) to react with D II cells.