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Guidelines for the use of fresh frozen plasma
Author(s) -
Ala F. A.,
Greaves M.,
Jones J.,
Levin M.,
Machin S. J.,
Morgan C.,
Murphy W.,
Napier J. A. F.,
Thomson A. R.
Publication year - 1992
Publication title -
transfusion medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.471
H-Index - 59
eISSN - 1365-3148
pISSN - 0958-7578
DOI - 10.1111/j.1365-3148.1992.tb00135.x
Subject(s) - fresh frozen plasma , medicine , thrombotic thrombocytopenic purpura , disseminated intravascular coagulation , cardiopulmonary bypass , coagulation , surgery , fluid replacement , intensive care medicine , anesthesia , platelet
SUMMARY. Fresh frozen plasma should only be used to treat bleeding episodes or prepare patients for surgery in certain defined situations. Definite indications for the use of FFP1 Replacement of single coagulation factor deficiencies, where a specific or combined factor concentrate is unavailable. 2 Immediate reversal of warfarin effect. 3 Acute disseminated intravascular coagulation (DIC). 4 Thrombotic thrombocytopenic purpura (TTP).Conditional uses: FFP only indicated in the presence of bleeding and disturbed coagulation1 Massive transfusion. 2 Liver disease. 3 Cardiopulmonary bypass surgery. 4 Special paediatric indications.No justification for the use of FFP1 Hypovolaemia. 2 Plasma exchange procedures. 3 ‘Formula’ replacement. 4 Nutritional support. 5 Treatment of immunodeficiency states.