Premium
The treatment of autoimmune thrombocytopaenic purpura with anti‐D immunoglobulin: similar platelet responses in homozygous and heterozygous Rh(D) positive patients
Author(s) -
Smith N. A.,
Boughton B. J.
Publication year - 1991
Publication title -
transfusion medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.471
H-Index - 59
eISSN - 1365-3148
pISSN - 0958-7578
DOI - 10.1111/j.1365-3148.1991.tb00029.x
Subject(s) - antibody , medicine , platelet , immunology , autoimmune thrombocytopenia , purpura (gastropod) , phenotype , biology , genetics , ecology , gene
Summary. Twenty‐one patients with autoimmune thrombocytopaenic purpura (AITP) were treated with anti‐D immunoglobulin. There was no significant difference with low and high dose anti‐D treatment in the platelet count response between homozygous and heterozygous Rh(D) positive patients. The heterogeneous responses seen in Rh(D) positive AITP patients treated with anti‐D immunoglobulin cannot therefore be explained by differences in Rh(D) phenotypes.