Premium
Signal Transduction via MHC Class‐I Molecules in T cells
Author(s) -
Tscherning T.,
Claësson M. H.
Publication year - 1994
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1994.tb03349.x
Subject(s) - major histocompatibility complex , microbiology and biotechnology , mhc class i , receptor , signal transduction , antigen presentation , biology , mhc class ii , cell , cell surface receptor , antigen , antigen presenting cell , t cell , immunology , genetics , immune system
SUMMARY The data reviewed in this paper, suggest that besides their role in presentation of antigenic pcptides to T cells, MHC‐I molecules may play an important role in the fine‐tuning of signal transmission across the cell membrane by their associations with a variety of cell‐surface receptors regulating cell growth and differentiation.