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The Interactions of γδ T Cells with Extracellular Matrix: Receptor Expression and Utilization Patterns
Author(s) -
WILKINS J.,
SELIN L.,
STEWART S.,
SIVANANTHAN K.,
STUPACK D.
Publication year - 1992
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1992.tb03093.x
Subject(s) - fibronectin , extracellular matrix , microbiology and biotechnology , adhesion , integrin , cell adhesion , matrix (chemical analysis) , extracellular , cell adhesion molecule , biology , receptor , chemistry , genetics , organic chemistry , chromatography
Purified populations and clones of human γδ T cells were examined for their ability to interact with extracellular matrix (ECM) components. The stimulation of these cells with phorbol ester induced cellular adhesion for ECM, The adhesion structures for fibronectin and collagen were shown to be members of the CD29 integrin family. The expression patterns of β1, β2 and β3, integrin‐s by these cells were examined. The receptor expression and utilization patterns suggest that αβ, γδ T cells and B cells have similar repertoires of adhesion structure.