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Serum Interleukin (IL‐1β) in Patients with Diffuse Scleritis
Author(s) -
PALEXAS G. N.,
PUREN A.,
SAVAGE N.,
WELSH N. H.
Publication year - 1992
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1992.tb01644.x
Subject(s) - scleritis , medicine , pathology , ophthalmology , uveitis
Scleritis is a painful, destructive inflammatory eye disease. We measured serum IL‐1β) in ten patients with diffuse scleritis and in control subjects matched for age and sex. Patients with diffuse scleritis were found to have significantly elevated serum concentrations of IL‐1/β in comparison to normal subjects ( P <0.02). The results suggest that IL‐l/β is associated with diffuse scleritis and may influence scleral breakdown in diffuse scleritis.