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The Leucocyte L1 Protein: Identity with the Cystic Fibrosis Antigen and the Calcium‐Binding MRP‐8 and MRP‐14 Macrophage Components
Author(s) -
ANDERSSON K. B.,
SLETTEN K.,
BERNTZEN H. B.,
DALE I.,
BRANDTZAEG P.,
JELLUM E.,
FAGERHOL M. K.
Publication year - 1988
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1988.tb02437.x
Subject(s) - complementary dna , peptide sequence , immunoglobulin light chain , macrophage , amino acid , amino terminal , biochemistry , calcium , antigen , calcium binding protein , microbiology and biotechnology , chemistry , biology , antibody , immunology , gene , organic chemistry , in vitro
The partial amino acid sequence of L1 protein light and heavy chains reveals an overall structure identical to the two macrophage proteins, MRP‐8 and MRP‐14, deduced from the sequence of the cDNA encoding the polypeptides. The light chain of L1 protein (L1‐L) was shown to contain two modified amino acid residues.