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Concanavalin‐A‐Activated Lymphocytes Suppress Immune Responses in Vitro but Are Helper Cells in Vivo
Author(s) -
MÖLLER G.
Publication year - 1985
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1985.tb01399.x
Subject(s) - concanavalin a , spleen , in vivo , in vitro , immune system , immunology , biology , microbiology and biotechnology , chemistry , biochemistry
In vitro concanavalin A (Con A)‐activaied spleen cells suppressed the primary in vitro immune response of syngeneic spleen cells to sheep erythrocytes (SRBC) but enhanced the in vivo anti‐SRBC responses when transferred to syngeneic untreated mice. Con‐A‐activated spleen cells injected into nude mice enabled these mice 10 respond to SRBC