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Family of Large Surface Proteins on Human Lymphocytes
Author(s) -
KOLLER B.,
DUNLAP B.,
HANK J.,
WEE S. L.,
BACH F.H.
Publication year - 1980
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1980.tb00102.x
Subject(s) - lactoperoxidase , population , polyacrylamide gel electrophoresis , microbiology and biotechnology , biochemistry , chemistry , cell , molecular mass , human blood , peripheral blood , polyacrylamide , human plasma , peptide , biology , enzyme , chromatography , immunology , medicine , peroxidase , physiology , environmental health
Cells surface molecules of T‐rosette‐positive human peripheral blood lymphocytes were labelled by lactoperoxidase and examined on 5% polyacrylamide gels. Several bands, ranging in molecular weight from 220,000 to 170,000 daltons, were seen. Analysis of the tryptic and chymotryptic digests of the 187K. 200K, 210K and 220K proteins indicated that they are of similar peptide composition. Study of clones derived from this population indicated that individual cells within a population differed in expression of these proteins.