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Detection of Fc Receptor‐bearing Lymphocytes by Using IgG‐coated Latex Particles
Author(s) -
SJÖBERG O.,
INGANÄS M.
Publication year - 1979
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1979.tb03283.x
Subject(s) - receptor , antibody , reproducibility , fc receptor , immunology , fragment crystallizable region , chemistry , microbiology and biotechnology , immunoglobulin g , chromatography , biology , biochemistry
Latex particles coated with human IgG can be used to detect lymphocytes capable of binding to the Fc portion of IgG, Optimal conditions are described. The method is as sensitive as techniques using antibody‐coated erythrocytes, is easy to perform, and has good reproducibility, A small proportion of T cells and the majority of B cells can be shown to carry receptors for Fc (IgG).