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Serial Measurements of Pregnancy‐specific β 1 ‐glycoprotein (β 1 SP 1 ) in Patients with Trophoblastic Disease
Author(s) -
SEARLE F.,
BAGSHAWE K. D.,
DENT J.,
LEAKE B. A.
Publication year - 1978
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1978.tb03981.x
Subject(s) - choriocarcinoma , radioimmunoassay , glycoprotein , pregnancy , andrology , medicine , detection limit , liter , gynecology , microbiology and biotechnology , biology , chemistry , chromatography , genetics
A radioimmunoassay for pregnancy‐specific‐β 1 ‐glycoprotein (Bohn. 1971) has been established with a limit of detection of 2 μMg/litre in serum. The assay has been used to measure serial levels of pregnancy‐specific‐β 1 ‐glycoprotein (β 1 SP 1 ) in the serum of patients with choriocarcinoma and teratoma for comparison with measurements of the β‐subunit of human chorionic gonadotrophin. The value of the assay for β 1 SP 1 , in the management of these patients is discussed.