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IgD and the Fetal Immune Response
Author(s) -
CEDERQVIST L. L.,
EWOOL L. C.,
LITWIN S. D.
Publication year - 1977
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1977.tb02156.x
Subject(s) - immunoglobulin d , cord blood , immunology , fetus , antibody , biology , cord , immune system , immunoglobulin m , immunoglobulin g , medicine , pregnancy , b cell , genetics , surgery
IgD was detected in 84% of cord sera at term by an inhibition‐of‐hemagglutination test, in contrast to low incidences reported earlier. Cord blood IgD and maternal serum IgD values were unrelated to each other, consistent with a fetal origin of the IgD. The cord blood IgD failed to correlate, either directly or inversely, with cord blood IgA or IgM, suggesting that its presence does not reflect fetal synthesis of specific antibody but rather may be developmental.