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Cellology of HLA II. Heterogeneity of Cellular Reactions in Negative HLA‐D Typing
Author(s) -
BRADLEY B. A.,
TERMIJTELEN A.
Publication year - 1977
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1977.tb02110.x
Subject(s) - human leukocyte antigen , typing , immunology , lymphocyte , tissue typing , biology , genetics , antigen
We have demonstrated that in more than half of the mixed lymphocyte reactions, proliferative reactions, in which responders were reacted against HLA‐D‐compatible homozygous typing cells, were significantly greater than zero. These reactions often masked the true HLA‐D identity of the cells under test, as was subsequently shown by primed lymphocyte testing.