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Cellology of HLA I. The Apparent Homogeneity of HLA‐D
Author(s) -
TERMIJTELEN A.,
BRADLEY B. A.
Publication year - 1977
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1977.tb02109.x
Subject(s) - human leukocyte antigen , homogeneous , immunology , typing , homogeneity (statistics) , biology , lymphocyte , genetics , antigen , mathematics , combinatorics , statistics
We have demonstrated that there is a similarity in the distribution of restimulation response of primed lymphocyte typing (PLT) cells raised between related and unrelated individuals, thus leading to the suggestion that HLA‐D is a homogeneous determinant. It is proposed that within HLA a hitherto unrecognized heterogeneous structure may exist that is closely associated wish HLA‐D and which may give rise to intermediate reactions in primary mixed lymphocyte reactions and PLT.