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Primed LD Typing: Reagent Preparation and Definition of the HLA‐D‐Region Antigens
Author(s) -
BACH F. H.,
JARRETTTOTH E. K.,
BENIKE C. J.,
SHIH C.Y.,
VALENTINE E. A.,
SONDEL P. M.,
BACH M. L.
Publication year - 1977
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1977.tb02105.x
Subject(s) - typing , antigen , human leukocyte antigen , immunology , haplotype , biology , histocompatibility testing , histocompatibility , microbiology and biotechnology , genetics , gene , allele
Primed LD typing cells were prepared against single HLA haplotypes within families and used to type a random panel of 48 individuals. PLT cells could be grouped on the basis of highly correlated responses with the panel test cells; the 21 different PLT cells could be used to define 6 different PL antigens. One of these, PL 3, was split by the responses of two of the 21 PLT cells which measured an antigen called PL 3.1.