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B‐Lymphocyte Alloantigens
Author(s) -
JOHNSON A. H.,
WARD F. E.,
AMOS D. B.
Publication year - 1977
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1977.tb02095.x
Subject(s) - locus (genetics) , biology , dig , antibody , lymphocyte , human leukocyte antigen , b cell , recombinant dna , cell , microbiology and biotechnology , genetics , immunology , antigen , gene
Seventy B‐cell alloantisera were tested by microcytotoxicity against a panel of B‐cell‐enriched and T‐cell‐enriched lymphocytes. Six groups were discerned and have tentatively been designated DIg 1–7 (for Duke immunoglobulin‐positive cell groups). These alloantisera were used to type an HLA‐A/B recombinant family. Two groups were observed to segregate in this family, DIg 7 with the HLA‐B locus and DIg 2 with the HLA‐A locus.