Premium
Evidence for Two Series of B‐Cell Antigens in Man and Their Comparison with HLA‐D
Author(s) -
ROOD J. J.,
LEEUWEN A.,
KEUNING J. J.,
THRMIJTELEN A.
Publication year - 1977
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1977.tb02092.x
Subject(s) - human leukocyte antigen , serology , antigen , immunology , locus (genetics) , antibody , biology , population , genetics , microbiology and biotechnology , medicine , gene , environmental health
Population mid family studies of five sera with antibodies against B‐cell determinants show an excellent fit of some of them with the HLA‐D determinants, suggesting that the HLA‐D determinants themselves or closely linked structures can be recognized by serology. One serum, Ag, might be coded for by a locus different from HLA‐D, which could be located between HLA‐A and ‐B, A two‐color fluorescence test to detect B‐cell antigens was used and found to save time and reagents and to give very good results.