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A High Molecular Weight Serum Protein Is the Carrier for Amyloid‐Related Protein SAA
Author(s) -
SKOGEN B.,
NATVIG J. B.,
MICHAELSEN T. E.,
ANDERS R. F
Publication year - 1977
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1977.tb00379.x
Subject(s) - amyloid (mycology) , serum amyloid a protein , serum amyloid a , chemistry , medicine , immunology , pathology , inflammation
In the present study evidence is presented that SAA in serum complexes to a carrier protein with a molecular weight of 100,000–200,000 daltons, with mobility in the a‐region on electrophoresis, and with a rather low normal strum concentration. The carrier protein is apparently not albumin. SAA isolated from the carrier protein has a molecular weight of 14,000 daltons and does not complex to any considerable extent with itself under neutral conditions.