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Generation of Cytotoxic T Lymphocytes Against Ly Alloantigen
Author(s) -
RÖLLINGHOFF M.,
PFIZENMAIER K.,
STARZINSKIPOWITZ A.,
WAGNER H.
Publication year - 1977
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1977.tb00350.x
Subject(s) - cytotoxic t cell , cyclophosphamide , immune system , in vivo , immunization , immunology , cytotoxicity , in vitro , biology , chemotherapy , genetics
Cytotoxic T lymphocytes specific for immune alloantigens controlled by alleles of the Ly system have been induced in vivo. These results were obtained either in a secondary type of response or by treating mice before immunization with a single dose of cyclophosphamide (80 mg/kg).