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The First Isoallotype of Human IgA Proteins
Author(s) -
LOGHEM E.,
LANGE G.,
KOISTINEN J.
Publication year - 1976
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1976.tb03003.x
Subject(s) - allotype , isotype , biology , antibody , immunology , monoclonal antibody
An antigenic determinant that occurs on all IgA proteins except on IgA2 proteins of the A2m2 allotype is described. The determinant is an isoallotype, being an isotype of IgA1 and at the same time an allotype of IgA2 proteins. It is proposed that the symbol nA2m2 be used for the new determinant, where n stands for isoallotype (formerly nonmarker) and A2m2 refers to the allotype to which it is antithetically related.