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Virus Antibody Levels and IgA Deficiency
Author(s) -
PYHÄLÄ R.,
AHO K.,
KANTANEN M.L.,
KOISTINEN J.
Publication year - 1976
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1976.tb00248.x
Subject(s) - mycoplasma pneumoniae , virology , virus , antibody , cytomegalovirus , biology , immunology , herpesviridae , medicine , viral disease , pneumonia
IgA‐deficient blood donors and their age‐ and sex‐matched controls were compared for the occurrence of complement‐fixing antibodies in serum against several viruses. The level in the IgA‐deficient persons was slightly higher against several respiratory pathogens (adenoviruses, type B influenza virus, parainfluenza virus, and respiratory syncytial virus) that give rise to localized infections, and against coxsackie B group of viruses. No corresponding difference was observed in mumps, varicella, and cytomegalovirus infections, where viraemia is a characteristic feature, or in Mycoplasma pneumoniae infection.