Premium
Glomerular Beta‐Lipoprotein in Childhood Renal Diseases
Author(s) -
FAULK W. PAGE,
McCORMICK J N,
GOODMAN J. R.,
PIEL C. F
Publication year - 1974
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1974.tb01300.x
Subject(s) - fibrinogen , nephrosis , glomerulonephritis , pathology , medicine , immunofluorescence , kidney , nephrotic syndrome , antibody , renal biopsy , immunology
Renal biopsies from 84 children, representing 8 diagnostic categories of kidney disease, were studied in the electron microscope and by immunofluorescence for evidence of IgG, IgM. IgA, complement, fibrinogen (Fib), and beta‐lipoprotein (BLp) The glomeruli of five patients, two of whom had glomerulonephritis; one, membranous glomerulonephritis; one, hemolytic uremic syndrome; and one, lipoidal nephrosis, contained BLp and Fib, and four of these also contained immunoglobulins and complement The BLp deposition in renal glomeruli was not clearly associated with either clinical or biochemical findings.