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Comparative efficacy of rHaa86 and rBm86 against Hyalomma anatolicum anatolicum and Rhipicephalus ( Boophilus ) microplus
Author(s) -
KUMAR B.,
AZHAHIANAMBI P.,
RAY D. D.,
CHAUDHURI P.,
De La FUENTE J.,
KUMAR R.,
GHOSH S.
Publication year - 2012
Publication title -
parasite immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.795
H-Index - 75
eISSN - 1365-3024
pISSN - 0141-9838
DOI - 10.1111/j.1365-3024.2012.01356.x
Subject(s) - biology , tick , rhipicephalus , hyalomma , rhipicephalus microplus , vaccination , larva , veterinary medicine , acari , zoology , ixodidae , immunology , virology , ecology , medicine
Summary Hyalomma anatolicum anatolicum and Rhipicephalus (Boophilus) microplus are the most economically important tick species in India and other tropical and subtropical regions of the world and transmit pathogens causing animal and human diseases. We demonstrated that vaccination of animal by rHaa86 could be used for the control of both H. a. anatolicum and R. (B.) microplus infestations. By comparing the efficacy of rHaa86 and rBm86, it was observed that vaccine based on rHaa86 will be more effective in controlling homologous challenge infestations (68·7% against larvae and 45·8% against adults). The results of this trial demonstrated that species‐specific antigens are the better choice for vaccine development and could serve as an effective tool for the integrated control of H. a. anatolicum .