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Interactions between schistosomiasis and infection with HIV‐1
Author(s) -
SECOR W. E.
Publication year - 2006
Publication title -
parasite immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.795
H-Index - 75
eISSN - 1365-3024
pISSN - 0141-9838
DOI - 10.1111/j.1365-3024.2006.00887.x
Subject(s) - schistosomiasis , immunology , biology , human immunodeficiency virus (hiv) , disease , helminthiasis , virology , environmental health , helminths , medicine
SUMMARY In many regions of the world, both schistosomiasis and HIV/AIDS are endemic, resulting in patients harbouring co‐infections. Because interaction with host CD4+T cells is a characteristic of schistosome as well as HIV‐1 infections, bi‐directional disease effects may be sufficiently different from sequelae caused by either infectious agent alone to warrant alteration of public health approaches in areas of co‐endemnicity. Studies published over the past decade provide useful insights into interactions between schistosomiasis and infection with HIV‐1, and overall support the hypothesis that special emphasis on treatment of schistosomiasis in populations with elevated prevalence or risk of HIV‐1 infection is justified.