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Detection of Bm86 antigen in different strains of Boophilus microplus and effectiveness of immunization with recombinant Bm86
Author(s) -
PENICHET MANUEL,
RODRIGUEZ MANUEL,
CASTELLANO ORLANDO,
MANDADO SARA,
ROJAS YOLANDA,
RUBIERA ROGER,
SANCHEZ PEDRO,
LLEONART RICARDO,
FUENTE JOSE DE LA
Publication year - 1994
Publication title -
parasite immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.795
H-Index - 75
eISSN - 1365-3024
pISSN - 0141-9838
DOI - 10.1111/j.1365-3024.1994.tb00377.x
Subject(s) - biology , recombinant dna , tick , antigen , immunization , vaccination , virology , immunology , gene , genetics
SUMMARY The control of tick populations by using conventional strategies poses several problems, including the appearance of organophosphate resistant strains, among others. The possibility of using alternative strategies such as vaccination with tick antigens has been suggested by several authors. One particular antigen (Bm86) has been described and shown to be able to induce a protective immunity against the cattle tick Boophilus microplus. In this paper we demonstrate by means of immunohistochemical staining that this antigen is conserved among several strains of this species. These results correlate with those showing that animals vaccinated with a preparation of recombinant Bm86 were protected against challenge with the four different strains tested, including one resistant to organophosphates. These results favour the immunization with recombinant Bm86 for the control of the cattle tick B. microplus.