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Distinction of human hookworm larvae based on lectin‐binding characteristics
Author(s) -
KUMAR SANJEEV,
PRITCHARD DAVID IDRIS
Publication year - 1992
Publication title -
parasite immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.795
H-Index - 75
eISSN - 1365-3024
pISSN - 0141-9838
DOI - 10.1111/j.1365-3024.1992.tb00464.x
Subject(s) - ancylostoma duodenale , necator americanus , biology , lectin , ancylostoma , ancylostomiasis , agglutinin , soybean agglutinin , ulex europaeus , immunology , helminths , ascaris lumbricoides
Summary A comparative study of lectin binding to ensheathed (EnL 3 ) and exsheathed (ExL 3 ) L 3 larvae of Necator americanus, Ancylostoma duodenale and Ancylostoma ceylanicum revealed a number of differences between these hookworm species. These differences could provide a novel approach to distinguish infective L 3 larvae in field conditions. For example, binding of Ulex europaeus agglutinin (UEA) and Ricinus communis agglutinin (RCA /20 ) to N. americanus EnL 3 distinguished them from those of A. duodenale and A. ceylanicum . Furthermore, UEA and RCA /20 negative EnL 3 could be separated into the two Ancylostoma sps. tested, as Dolichos biflorus agglutinin and Soybean agglutinin bound to EnL 3 of A. ceylanicum but not to those of A. duodenale .