Premium
An immunocytochemical test for the diagnosis of antibodies to Plasmodium vivax
Author(s) -
BRACHO CARMEN,
PEREZ HILDA
Publication year - 1992
Publication title -
parasite immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.795
H-Index - 75
eISSN - 1365-3024
pISSN - 0141-9838
DOI - 10.1111/j.1365-3024.1992.tb00022.x
Subject(s) - plasmodium vivax , biology , antibody , serology , malaria , immunology , virology , antigen , parasite hosting , plasmodium falciparum , world wide web , computer science
Summary An immunocytochemical peroxidase test (ICPT) has been developed to allow serological measurement of the antibody response to Plasmodium vivax by light microscopy. Acetone fixed P. vivax erythrocyte stages were used as source of antigen. The immunofluorescent antibody test (IFAT) was used as reference test. In testing sera from individuals infected with P. vivax in southeastern Venezuela a high correlation (100%) was obtained between the ICPT and the IFAT. There were cross reactions with sera from patients with malaria by P. falciparum but not with those from patients with other parasitic diseases. Antibody titres as measured by the ICPT showed a positive correclation with past P. vivax malarial experiences.