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Non‐specific resistance of sheep against Haemonchus conforms with Freund's complete adjuvant
Author(s) -
BAUTISTAGARFIAS C.R.,
FLORESHERNANDEZ O.,
QUIROZROMERO H.
Publication year - 1991
Publication title -
parasite immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.795
H-Index - 75
eISSN - 1365-3024
pISSN - 0141-9838
DOI - 10.1111/j.1365-3024.1991.tb00552.x
Subject(s) - haemonchus contortus , adjuvant , biology , veterinary medicine , immunology , medicine , helminths
Summary Six groups of four ovines each were injected intraperitoneally with Freund's complete adjuvant (FCA), at various limes before, during, or after infection with 10000 larvae (L 3 ) of Haemanchus contortus per sheep. Animals in groups A and B received FCA on days 14 and 7, respectively, before infection. Ovines in group C were treated with FCA on the same day of infection; while sheep in groups D, E. and F were injected with the adjuvant on days 7. 14. and 21, respectively, after infection. Significant reductions in adult worm numbers compared with non‐treated controls, as determined 42 days after infection, were of 30%, 34%, 45%. 52%, 56%, and 55% in groups A, B, C, D, E, and F, respectively. A significant correlation, between the time of FCA administration (referred to the day of infection) and the number of worms recovered at necropsy, was also observed.