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Specific cross‐protection between Schistosoma bovis and S. haematobium induced by highly irradiated infections in mice
Author(s) -
AGNEW ALISON M.,
MURARE H. M.,
DOENHOFF M. J.
Publication year - 1989
Publication title -
parasite immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.795
H-Index - 75
eISSN - 1365-3024
pISSN - 0141-9838
DOI - 10.1111/j.1365-3024.1989.tb00672.x
Subject(s) - biology , schistosoma haematobium , schistosomiasis , schistosoma mansoni , schistosoma , immunology , helminthiasis , virology , homologous chromosome , helminths , genetics , gene
Summary Significant levels of resistance against Schistosoma haematobium challenge were developed by mice exposed to highly irradiated (20 krad) cercariae of the homologous species (46–53%) or of the closely related species, S. hovis (34–56%) but not of S. mansoni (– 6–28%). This ability to cross‐protect reflects the phylogenetic relationships between these species; S. mansoni and S. bovis , as well as S. mansoni and S. haematobium , failed to cross‐protect. The cross‐protection demonstrated between S. bovis and S. haematobium in mice was non‐reciprocal.