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IgE production in rat fascioliasis
Author(s) -
PFISTER K.,
TURNER K.,
CURRIE A.,
HALL E.,
JARRETT E.E.E.
Publication year - 1983
Publication title -
parasite immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.795
H-Index - 75
eISSN - 1365-3024
pISSN - 0141-9838
DOI - 10.1111/j.1365-3024.1983.tb00775.x
Subject(s) - biology , immunoglobulin e , hepatica , immunology , parasite hosting , helminthiasis , parenchyma , fasciola hepatica , liver fluke , parasitic infection , helminths , antibody , botany , world wide web , computer science
Summary F. hepatica infection of rats caused a prolonged elevation of serum total IgE reflecting the continued presence of live worms in the host. Infection with 40 metacercariae stimulated higher total IgE levels than infection with 20 metacer‐cariae. The parasite specific IgE response was biphasic, the first peak coinciding with the migratory phase in the liver parenchyma and the second with the establishment of flukes in the bile ducts.