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Natural agglutinins to African trypanosomes
Author(s) -
FERRANTE A.,
ALLISON A.C.
Publication year - 1983
Publication title -
parasite immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.795
H-Index - 75
eISSN - 1365-3024
pISSN - 0141-9838
DOI - 10.1111/j.1365-3024.1983.tb00770.x
Subject(s) - biology , antibody , trypanosoma , immunology , glycoprotein , opsonin , protozoa , trypanosoma brucei , virology , microbiology and biotechnology , biochemistry , gene
Summary Agglutinins to uncoated culture forms of the African trypanosomes, T. congolense and T.b. brucei were detected in sera from a variety of mammals not exposed to the parasites. The agglutinins in bovine serum were shown to be specific antibodies with opsonic properties selective for the species of trypano‐some. These findings suggest a possible role for the glycoprotein coat in preventing access of cross‐reacting antibodies to the plasma membrane of African trypanosomes.